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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
Postnatal

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdkn2a  cyclin dependent kinase inhibitor 2A   (Synonyms: Arf, ARF-INK4a, Ink4a/Arf, INK4a-ARF, MTS1, p16, p16INK4a, p19ARF, p19, Pctr1)
Results  Reference
1J:167536 Abbas HA, Maccio DR, Coskun S, Jackson JG, Hazen AL, Sills TM, You MJ, Hirschi KK, Lozano G, Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell. 2010 Nov 5;7(5):606-17
1J:96524 Bengtsson T, Aszodi A, Nicolae C, Hunziker EB, Lundgren-Akerlund E, Fassler R, Loss of {alpha}10{beta}1 integrin expression leads to moderate dysfunction of growth plate chondrocytes. J Cell Sci. 2005 Mar 1;118(Pt 5):929-36
1J:144496 Chatoo W, Abdouh M, David J, Champagne MP, Ferreira J, Rodier F, Bernier G, The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity. J Neurosci. 2009 Jan 14;29(2):529-42
1J:282259 Gal H, Lysenko M, Stroganov S, Vadai E, Youssef SA, Tzadikevitch-Geffen K, Rotkopf R, Biron-Shental T, de Bruin A, Neeman M, Krizhanovsky V, Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019 Sep 16;38(18):e100849
1J:246072 Golson ML, Dunn JC, Maulis MF, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, Gannon M, Activation of FoxM1 Revitalizes the Replicative Potential of Aged beta-Cells in Male Mice and Enhances Insulin Secretion. Diabetes. 2015 Nov;64(11):3829-38
1*J:147752 Gromley A, Churchman ML, Zindy F, Sherr CJ, Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6285-90
1J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028
1J:191599 Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM, Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol. 2012 Dec;132(12):2681-90
1J:298947 Liu H, Hilliard S, Kelly E, Chen CH, Saifudeen Z, El-Dahr SS, The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice. J Biol Chem. 2020 Aug 14;295(33):11542-11558
1J:217690 Lopez-Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman AC, Gutarra S, Gonzalez S, Munoz-Canoves P, Fernandez-Salguero P, Radtke F, Bigas A, Espinosa L, Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015 Jan 1;142(1):41-50
1J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819
1J:175603 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA, Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 2011;30(17):3635-46
1J:335234 Parveen N, Wang JK, Bhattacharya S, Cuala J, Singh Rajkumar M, Butler AE, Wu X, Shih HP, Georgia SK, Dhawan S, DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-cell Heterogeneity. Diabetes. 2023 Jan 6;72(5):575-89
1J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3)
1J:99492 Schmetsdorf S, Gartner U, Arendt T, Expression of cell cycle-related proteins in developing and adult mouse hippocampus. Int J Dev Neurosci. 2005 Feb;23(1):101-12
1J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory